Comparing the protective effect of the conventional pasteurized and lactobacillus acidophilus-fortified pasteurized yoghurts on candida albicans

Statement of Problems: Candida species are the most common fungal pathogen in human's body. Therefore an accurate and immediate treatment seems to be necessary. Nowadays, alternative treatments, such as probiotics, are considered because of the adverse side effects of chemical medications. Probiotics are alive organisms which can be used for medical purposes and are added to different kinds of diary such as yoghurt. Lactobacill Acidophilus [LA] was detected form human's recourses many years ago and nowadays can be found in special kinds of milk, yoghurt, juice and food complementories

Purpose: In this study we are to compare the effect of conventional pasteurized and lactobacillus acidophilus- fortified pasteurized yoghurt on Candida Albicans in vitro

Materials and Method: Candida Albicans was isolated from 30 oral candidasis patients, cultured and prepared as standard suspension. Probiotic powder of LA in MRS Media after 24hrs led to 5x10[9] lactobacillus. LAfortified yoghurt was prepared via adding lactobacills into 250 ml of pasteurized boiled milk after 8hrs in 37[degree]c. We prepared 3 tubes and added standard suspension of Candida in each of them. Adding sterile yoghourt, conventional pasteurized yoghurt and LAfortified yoghurt to the tubes respectively, we put them in 35[degree]c incubator for 48 hrs. We added the content of each tube in Sabouraud agar media and incubated in 25[degree]c for 72 hrs and then counted the colonies

Results: There was a significant difference between the mean of colonies in each group during 5 days [p = 0, df = 4] and also on each day [p = 0, df = 2]

Conclusion: L.A. can inhibit colonization of Candida in vitro. In this study the most of Candida colonies were in the sterile yoghurt and the least of them were in LA fortified yoghurt

Comparing the effect of phenytoin syrup and triamcinolone acetonide ointment on aphthous ulcers in patients with Behcet's syndrome

Recurrent aphthous stomatitis [RAS] appears to be the most common type of oral ulcers. The lesion is usually self limited but its painful presentation results in some difficulties. Therefore, an efficient therapeutic strategy is required and currently existing therapies seem to be inadequate because of its unclear etiology. Here the therapeutic effect of triamcinolone acetonide ointment as a relatively expensive medication has been compared with phenytoin syrup on aphthous ulcers in patients with Behcet's syndrome. Thirty out of 60 our patients with Behcet's syndrome were randomly treated by phenytoin syrup and the remaining were advised to use 0.1% triamcinolone acetonide ointment. After a week, they were visited again to determine the status of aphthous ulcers. Positive response in the triamcinolone acetonide group and phenytoin group was 86.7% and 53.3%, respectively. The effectiveness of triamcinolone acetonide ointment was more than phenytoin on aphthous ulcers in patients with Behcet's syndrome

[Evaluation of the relationship between oral lichen planus and stress]

Statement of Problem: Psychosomatic factors and their association with dermatological disorders are well recognized; yet, their importance in oral lichen planus [OLP] is still debated

Purpose: This study was done to determine the importance of stress in patients with OLP

Materials and Method: In this cross-sectional case control study, the control group consisted of 47 apparently healthy patients without any mucosal lesion, and the experimental group consisted of 52 biopsy proven OLP subjects [28 erosive lichen planus and 24 reticular form] which were age and sex matched with the control group. They were referred to department of oral medicine in Tabriz University of Medical Science during May 2008-July 2008. The General Health Questionnaire-version 12 [GHQ-12] and the Perceived Stress Scale [PSS] were used to evaluate stress in OLP patients and control group. The data were analyzed through Kruskal-Wallis and Man Whitney tests. P value less that 0.05 was considered as significant

Results: The patients with erosive lichen planus had significantly more stress [Z = 4.123; p < 0.05] than the controls. Similar findings were noted between the reticuler lichen planus and control group [Z = 5.891; p < 0.05]. However, the differences in stress [Z = 2.248; p > 0.05]was found to be non-significant between the patients with erosive lichen planus and reticular form

Conclusion: A significantly higher level of stress was found in the OLP patients [both erosive and reticular form] than the control group, but no significant difference was noted between the patients with erosive lichen planus and reticular form. Therefore it can be concluded that psychological stressors play an important role in the creating OLP

relationship between geographic tongue and stress

Geographic tongue [GT] is a fairly common and usually asymptomatic disorder that is often detected on routine dental examinations. Characteristic lesions appear as multiple, well-demarcated zones of erythema, concentrated at the tip and lateral borders of tongue. Although the etiology of the condition is unknown, it may be related to stress. The purpose of this study was to evaluate the association between GT and stress. This study was performed on 60 patients with GT and 60 patients without GT. All the patients filled a questionnaire and a psychologist evaluted them. The total mean score of stress was 19.8 in GT group and 15.8 in the control group. According to the results, there is an association between stress and GT. Decreasing stress in GT patients can lead to the healing of the lesion. Other factors that may be associated with GT should be studied in future

Oral manifestations of Ehlers-Danlos syndrome and presentation of a case

Ehlers-Danlos syndrome [EDS] is a rare syndrome, primarily diagnosed by clinical findings and family history. The clinical manifestations of EDS in the orofacial region consist of extra-oral and intra-oral manifestations. Its prognosis depends on the [sub] type and the proper, early diagnosis of the syndrome. The purpose of the present paper is to discuss the manifestations of this syndrome, especially its oral manifestations, and to present a case

effect of citalopram and colonazpam on burning mouth syndrome

Psychosocial factors are thought to play a role in burning mouth syndrome [BMS] and several therapeutic approaches for BMS are based on this consideration. This paper evaluated the efficacyof the combined systemic administration of citalopram and clonazepam, as anti-depressant and anti-anxiety drugs, in the management of burning mouth syndrome and reduction of the burning sensation. In this cross-sectional study, 80 subjects suffering from idiopathic burning mouth syndrome were enrolled. The patients underwent a thorough clinical examination. Oral symptoms before and after treatment were assessed using a Visual Analogue Scale. The mean duration of burning in our patients was 7 months. Systemic combination of citalopram [20mg/daily] and clonazpam [0.25 mg/daily] was prescribed for all of them for 8 weeks. Then, the data were analysed, using Student's t-test. Of the 62 patients who completed the protocol, 38 reported complete remission of the oral burning sensation. However, 20 patients reported a little improvement, and four of them reported no improvement. These data suggest that citaloperam with colonazpam is effective in patients with BMS